Abstract
Assisted reproductive technologies (ART) are performed around the world with more than 100,000 pregnancies achieved annually. This review aims to outline the nature of pregnancy loss in pregnancies conceived following ART as a result of biochemical pregnancy loss, clinical miscarriage, ectopic pregnancy, later fetal loss and perinatal death. Up to 25% of ART pregnancies are lost before the end of the first trimester, with an additional 2–4% lost later in the pregnancy. Furthermore, the increased rates of multiple pregnancies, prematurity and congenital abnormality all contribute to this increased risk. The role of ART in the etiology of pregnancy loss is also discussed.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.