![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
Corneal disease is the primary cause of visual loss in allergic eye disease. It occurs almost exclusively in vernal keratoconjunctivitis and atopic keratoconjunctivitis. It is characterized by punctate and then confluent corneal ulceration, plaque formation, increased risk of corneal infection and abnormalities of corneal shape. It is related to the degree of conjunctival inflammation and largely controlled by inflammatory mediators in the tear film. Other contributing causes are changes in corneal sensation, tear film, and the immune response of resident corneal cells. Corneal disease in vernal keratoconjunctivitis and atopic keratoconjunctivitis currently requires aggressive treatment with topical steroids. In the future, better identification of the undesirable immune response in individual patients will allow targeting of anti-inflammatory treatment with fewer side effects.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.