Keratoconus: prevalence and associations

Abstract

Evaluation of: Xu L, Wang YX, Guo Y, You QS, Jonas JB; the Beijing Eye Study Group. Prevalence and associations of steep cornea/keratoconus in Greater Beijing. The Beijing Eye Study. PLoS One 7(7), e39313 (2012).

According to the Beijing Eye Study, which was conducted in Chinese adults over the age of 50 years living in Greater Beijing (with steep cornea/keratoconus as corneal refractive power of ≥48 diopters), the prevalence of steep cornea/keratoconus was reported to be 0.9 + 0.2%. The prevalence of steep cornea/keratoconus was significantly associated with the ocular parameters of shorter axial length, smaller interpupillary distance, higher cylindrical, myopic refractive error and lower best corrected visual acuity. None of the systemic parameters were tested, such as gender, body height, psychic depression, cognitive function, blood concentrations of glucose, lipids, creatinine and C-reactive protein, blood pressure, quality of life score or ocular factors, such intraocular pressure, dry-feeling eyes, and lens thickness, showed any significant association with steep cornea/keratoconus.

Keywords::

• associations
• keratoconus
• prevalence

Financial & competing interests disclosure

The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.