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Perspective

Is antibiotic resistance a problem in the treatment of ophthalmic infections?

Pages 119-126 | Published online: 09 Jan 2014
 

Abstract

Antibiotic resistance is a world-wide problem of systemic medicine, but it appears to be less problematic in the treatment of ophthalmic infections. The use of topical administration and intraocular injection of antibiotics provides very high antibiotic concentrations in the ocular tissues. These high concentrations are effective in treating bacteria that are deemed resistant using standard interpretations of susceptibility. Although in vitro bacterial resistance, based on serum standard interpretation, is reported for ocular bacteria, these isolates are generally not spread from patient-to-patient and there are antibiotics available to effectively treat and overcome the false resistance.

Financial & competing interests disclosure

The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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