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Key Paper Evaluation

Improving risk stratification for cardiovascular disease

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Pages 1091-1093 | Published online: 10 Jan 2014
 

Abstract

Evaluation of: Heslop CL, Frohlich JJ, Hill JS. Myeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiography. J. Am. Coll. Cardiol. 55(11), 1102–1109 (2010).

Identifying people at high risk of cardiovascular events is the cornerstone of cardiovascular disease prevention and a major challenge for healthcare worldwide. Recently, both inflammatory and oxidative markers have been shown to improve cardiovascular risk prediction models in a wide range of patients. Here, we evaluate a recent publication investigating the value of inflammatory and oxidative markers for the prediction of cardiovascular mortality in patients with stable coronary artery disease. This study shows that the use of multiple markers may increase the predictive power of traditional risk models. The findings are discussed in the context of cardiovascular risk prediction in general.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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