Financial & competing interests disclosure
This work was supported by grants from the Medical Research Council (G0902037), British Heart Foundation (RG/07/008/23674), Stroke Association, National Heart Lung and Blood Institute (5RO1 HL036310), National Institute on Aging (R01AG034454, 5RO1AG13196) and Agency for Health Care Policy Research (5RO1AG034454), the Academy of Finland (projects 124271, 124322, 126602, 129262 and 132944), and the European Union New OSH ERA Research. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.