Financial & competing interests disclosure
This work was performed in the context of the Escher project (T6-202), a project of the Dutch Top Institute Pharma (TI Pharma). TI Pharma is a consortium of public partners, private partners and the Dutch government. TI Pharma did not play a role in the design, conduct or analysis, or interpretation of the data, or in the writing or review of the manuscript. H Schellekens has participated in meetings and publications sponsored by the pharmaceutical industry. His work on this study did not include a third party in any way. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.