DBHR: a Collection of Databases Relevant to Human Research

Abstract

Background: The achievement of the human genome project provides a basis for the systematic study of the human genome from evolutionary history to disease-specific medicine. With the explosive growth of biological data, a growing number of biological databases are being established to support human-related research. Objective: The main objective of our study is to store, organize and share data in a structured and searchable manner. In short, we have planned the future development of new features in the database research area. Materials & methods: In total, we collected and integrated 680 human databases from scientific published work. Multiple options are presented for accessing the data, while original links and short descriptions are also presented for each database. Results & discussion: We have provided the latest collection of human research databases on a single platform with six categories: DNA database, RNA database, protein database, expression database, pathway database and disease database. Conclusion: Taken together, our database will be useful for further human research study and will be modified over time. The database has been implemented in PHP, HTML, CSS and MySQL and is available freely at https://habdsk.org/database.php.

Lay abstract

We have compiled the most recent collection of human research datasets into six categories – DNA database, RNA database, protein database, expression database, pathway database and disease database – on a single platform. In all, 680 human datasets were acquired and incorporated from scientifically published studies. There are several ways to retrieve the data, as well as original links and short descriptions for each database. The primary goal of our research is to store, organize and exchange data in an organized and searchable format. In brief, we have planned the future development of additional features in the database. Our database will be beneficial for future human research studies and will be updated throughout time. We firmly believe that every researcher should have access to essential biological databases, so we have gathered a collection of human-related databases that are regularly used and currently available but have not previously been presented in such a simple and welcoming manner.

Keywords:

• DBHR
• DNA database
• human database
• human genome
• protein database

Supplementary data

To view the supplementary data that accompany this paper please visit the journal website at: www.tandfonline.com/doi/suppl/10.4155/fsoa-2021-0101

Author contributions

Dr. Shahid Ullah designed and supervised the project with Dr. Tianshun Gao's assistance, performed data analysis. Farhan Ullah, Wajeeha Rahman, Muhmmad Ijaz and Gulzar Ahmad contributed to data analysis. Shahid Ullah wrote the manuscript. All authors reviewed the manuscript.

Acknowledgments

To avoid future conflict, we would like to say that our database is uploaded on S Khan Lab website http://www.habdsk.org/database.php, so that we have provided some content in this article. A warm welcome to Ramish Durran Khan, who joined us on 15 December 2021.

Financial & competing interests disclosure

This project is supported by National Natural Science Foundation of China (32100434) and Shenzhen’s introduction of talents and research start-up (392020). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.