Fetal Supraventricular Tachycardia and Maternal COVID-19 Vaccination: is There Any relationship?

Abstract

Fetal supraventricular tachycardia accounts for 60–80% of the fetal tachyarrhythmias with prevalence ranging from 1/1000 to 1/25 000 pregnancies. It may be secondary to fetal anomalies or maternal factors. By reviewing the literature, there is no previous article that reports fetal arrhythmia after maternal vaccination. We present herein two cases of fetal supraventricular tachycardia following the administration of the Pfizer-BioNTech COVID-19 vaccine during pregnancy. Continued safety monitoring and more longitudinal follow-up are needed to evaluate the fetal impact after maternal COVID-19 vaccination.

Plain Language Summary

In the setting of the worldwide high surge of COVID-19 infection, vaccination of pregnant women is still debatable. By reviewing the literature, there is no previous article that reports fetal arrhythmia after maternal vaccination. We present herein two cases of fetal supraventricular tachycardia following the administration of the Pfizer-BioNTech COVID-19 vaccine during pregnancy. Continued safety monitoring and more longitudinal follow-up are needed to evaluate the fetal impact after maternal COVID-19 vaccination.

Keywords:

• COVID-19 vaccine
• fetal arrhythmia
• pregnancy
• supraventricular tachycardia

Author contributions

All authors have contributed equally in the literature search and redaction of this article.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

Informed consent disclosure

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional research committee and with the Helsinki declaration. An informed consent has been obtained from all the participants involved. The authors state that they have obtained verbal and written informed consent from the patient/patients for the inclusion of their medical and treatment history within this case report.