A Rare Case of Gastric Metastasis Originating From Primary Lung Adenocarcinoma: a Case Report

Abstract

Unlike liver and lung, the stomach is rarely a metastatic location for cancers. We report a case of a 62-year-old man known to have lung adenocarcinoma poorly differentiated presented with melena 1 month after diagnosis. Upper endoscopy revealed an ulcerated tumor in the prepyloric antrum. The diagnosis of gastric metastasis from pulmonary cancer was confirmed by the immunohistochemical staining for the thyroid transcriptional factor-1 and the pattern cytokeratine CK7+/CK20-. In conclusion, gastric metastasis from primary lung cancer is a rare phenomenon that every clinician must keep in mind.

Plain Language Summary

A 62-year-old man known to have lung adenocarcinoma poorly differentiated presented with melena 1 month after diagnosis. Upper endoscopy revealed an ulcerated tumor in the prepyloric antrum. The diagnosis of gastric metastasis from pulmonary cancer was confirmed by histology.

Keywords:

• gastric metastasis
• immunochemistry
• lung cancer

Author contributions

M Moalla, A Khsiba, N Abid and A Douggaz: have made substantial contributions to conception and design, or acquisition of data or analysis and interpretation of data. M Moalla, A Khsiba and H Belfkih: been involved in drafting the manuscript or revising it critically for important intellectual content. M Mahmoudi, AB Mohamed, M Yacoubi, M Medhioub, L Hamzaoui, E Chelbi and MM Azouz: have participated sufficiently in the work to take public responsibility for appropriate portions of the content. M Moalla, A Khsiba and MM Azouz: agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

Informed consent disclosure

The authors state that they have obtained verbal and written informed consent from the patient/patients for the inclusion of their medical and treatment history within this case report.