Inverse Psoriasis: From Diagnosis to Current Treatment Options

Abstract

Inverse psoriasis represents a clinical variant of psoriasis that is sometimes difficult to diagnose due to its clinical similarity with other skin disorders involving the folds, mainly including mechanical intertrigo, fungal and bacterial infections, contact dermatitis, seborrheic dermatitis, and lichen planus. Dermoscopy represents a useful tool for an enhanced non-invasive diagnosis. The treatment of inverse psoriasis may be challenging and include topical corticosteroids, topical calcineurin inhibitors, vitamin D analogs, traditional oral systemic therapies such as cyclosporine and methotrexate, and biologic therapies.

Keywords:

• psoriasis
• inverse
• diagnosis
• dermoscopy
• confocal microscopy
• treatment

Disclosure

Maria Letizia Musumeci reports personal fees from Abbvie, personal fees from Biogen, personal fees from Janssen Cilag, personal fees from Eli Lilly, personal fees from Novartis, outside the submitted work. The authors report no other conflicts of interest in this work.