Weight loss in elderly women in low-level care and its association with transfer to high-level care and mortality

Abstract

Background

The purpose of this study was to determine whether unintentional weight loss in older women predicts an imminent transition out of low-level care (either to higher-level care or by mortality).

Methods

Fifty-three Australian women, ambulatory while living in low-level care and requiring minimal assistance, were studied. At baseline, when the women were aged (mean ± standard deviation) 86.2 ± 5.3 years, body composition was assessed by dual energy X-ray absorptiometry, dietary intake was determined by a three-day weighed food record, a venous blood sample was taken, and both muscle strength and physical functioning were measured. The women were then followed up for 143 weeks to record the composite outcome of transfer to high-level care or mortality.

Results

During follow-up, unintended loss of body weight occurred in 60% of the women, with a mean weight loss of −4.6 ± 3.6 kg. Seven women (13.2%) died, and seven needed transfer to high-level care. At baseline, those who subsequently lost weight had a higher body mass index (P < 0.01) because they were shorter (P < 0.05) but not heavier than the other women. Analysis of their dietary pattern revealed a lower dietary energy (P < 0.05) and protein intake (P < 0.01). The women who lost weight also had lower hip abductor strength (P < 0.01), took longer to stand and walk (P < 0.05), and showed a slower walking speed (P < 0.01). Their plasma C-reactive protein was higher (P < 0.05) and their serum albumin was lower (P < 0.01) than women who did not lose weight. Nonintentional weight loss was a significant predictor of death or transfer to high care (hazards ratio 0.095, P = 0.02).

Conclusion

Weight loss in older women predicts adverse outcomes, so should be closely monitored.

Keywords:

• aged care
• weight loss
• mortality
• high care

Acknowledgments

We would like to thank staff and residents of the aged care facilities for their cooperation and participation in the study. We would also like to acknowledge research nurses, Sheila Matthews, Judy Tan, and Kylie King, who sourced medical data on residents, and Bereha Khorda for performing muscle strength and functional testing. The larger trial in which this study was nested was funded by Dairy Australia.

Disclosure

The authors report no conflicts of interest in this work.