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Review

The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection

, , , , , & show all
Pages 149-156 | Published online: 11 Feb 2013
 

Abstract

The ubiquitous distribution of vitamin D receptors in the human body is responsible for the pleiotropic effects of vitamin D-receptor activation. We discuss the possible beneficial effects of a selective activator of vitamin D receptor, paricalcitol, on the cardiovascular system in chronic heart failure patients and chronic kidney patients, in light of new trials. Paricalcitol should provide additional clinical benefits over the standard treatment for chronic kidney and heart failure, especially in cases of cardiorenal syndrome.

Disclosure

The authors report no conflicts of interest in this work.