Resistance training improves isokinetic strength and metabolic syndrome-related phenotypes in postmenopausal women

Abstract

Purpose

To examine the effects of resistance training (RT) on metabolic syndrome-related phenotypes in postmenopausal women.

Patients and methods

Twenty-two postmenopausal women (65.0±4.2 years) underwent 12 weeks of whole body progressive training with intensity prescribed based on rating of perceived exertion. Dominant knee extension strength was assessed using an isokinetic dynamometer before and after the intervention. Moreover, all volunteers had blood samples collected for lipid profile, glycemic control, and C-reactive protein analyses. Waist circumference and arterial blood pressure were also measured at baseline and after the training period. Student’s t-tests for paired samples and repeated measures ANOVA were used to compare dependent variables, and statistical significance was set at P<0.05.

Results

Isokinetic muscle strength significantly increased (P<0.01) with training. It was observed that waist circumference as well as total and low-density lipoprotein cholesterol levels significantly decreased with training (P<0.01). Total cholesterol/high-density lipoprotein cholesterol ratio, an important marker of cardiovascular disease incidence, was also significantly reduced (from 3.91±0.91 to 3.60±0.74; P<0.01) after the program. Blood glucose, basal insulin, and homeostatic model assessment of insulin resistance were also significantly reduced (P<0.01). No significant alterations were observed for resting blood pressure, triglycerides, or C-reactive protein.

Conclusion

Based on the observed results, it can be concluded that a 12-week progressive RT program, besides increasing isokinetic muscle strength, induces beneficial alterations on metabolic syndrome-related phenotypes in postmenopausal women. These findings highlight this mode of exercise as an important component of public health promotion programs for aged women. RT improves isokinetic strength and metabolic syndrome-related phenotypes in postmenopausal women.

Keywords:

• strength training
• cardiometabolic risk
• OMNI-RES
• aging

Acknowledgments

We thank the participants of the study and the Sabin Laboratory, which allowed analyses of blood variables. This work was supported by National Council for Scientific and Technological Development grants 487622/2012-0 and 307630/2013-7 by University of Brasília.

Disclosure

The authors report no conflicts of interest in this work.