Late-life depression with comorbid cognitive impairment and disability: nonpharmacological interventions

Abstract

Less than half of older adults with depression achieve remission with antidepressant medications, and rates of remission are even poorer for those with comorbid conditions. Psychosocial interventions have been effective in treating geriatric depression, either alone or better yet, in combination with antidepressant medications. Traditional strategies for nonpharmacological treatment of late-life depression do not specifically address the co-occurring cognitive impairment and disability that is prevalent in this population. Newer therapies are recognizing the need to simultaneously direct treatment efforts in late-life depression towards the triad of depressive symptoms, cognitive dysfunction, and functional disability that is so often found in geriatric depression, and this comprehensive approach holds promise for improved treatment outcomes.

Keywords:

• geriatric depression
• dementia
• functional impairment
• psychotherapy

Acknowledgements

Dimitris Kiosses is supported by a grant from the National Institute of Mental Health K23MH074659.

Disclosure

The authors report no conflicts of interest in this work.