Giant Intraparenchymal Meningioma in a Female Child: Case Report and Literature Review

Abstract

Background

Intraparenchymal meningiomas without dural attachment are extremely rare, especially in female children. To our knowledge, fibrous intraparenchymal meningioma located in the temporal lobe has never been reported in female children. The significance in the differential diagnosis of lesions in the temporal lobe should be emphasized.

Case Presentation

A 12-year-old girl was admitted to our hospital, complaining of recurrent generalized seizures for 2 months. Magnetic resonance imaging demonstrated a solid lesion located in the temporal lobe. The lesion underwent gross total resection. Histopathological examination indicated that the lesion was a fibrous meningioma. Postoperative rehabilitation was uneventful.

Conclusion

This case report presents an extremely unusual intraparenchymal fibrous meningioma of the temporal lobe with peritumoral edema and reviewed 21 intraparenchymal meningioma cases in children and to discuss the clinical presentation and treatment, differential diagnosis, and radiological features.

Keywords:

• meningioma
• fibrous
• temporal lobe
• intraparenchymal

Acknowledgments

The authors would also like to acknowledge the surgeons, nurses, and pathologists who helped to manage patients and provide pathological images.

Abbreviations

MRI, Magnetic resonance imaging; CT, Computerized Tomography STR, subtotal resection; GTR, gross total resection; MCA, middle cerebral artery; ACA, anterior cerebral artery; NF2, neurofibromatosis type 2; MRA, MR Angiography; CTA, CT angiography; ICA, internal carotid artery; NF2, neurofibromatosis type 2; MRS: MR spectroscopy; ASL, Arterial spin labeling; CBF, cerebral blood flow; rCBF, relative cerebral blood flow; rCBV, relative cerebral blood volume; SSTR II, Somatostatin receptor II; PET, positron emission Tomography; Ga-68, gallium-68.

Ethics Approval and Consent to Participate

This study was approved by the Ethics Committee of Henan University People’s Hospital, and informed consent was obtained from parents and legal guardians.

Consent for Publication

We have obtained consent for publication from parents and legal guardians.

Author Contributions

All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work. Yushe Wang, and Yong Wang contributed to the conception of the study. Shuo Wen and Hao Liang collected the data. Huachao Guo wrote the manuscript. Jiaguang Wang took part in drafting. Zhen Ma contributed significantly to analysis and manuscript preparation; All authors read and approved the final manuscript.

Disclosure

The authors declare that they have no competing interests.