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Page 186, Disclosure, the text “The authors report no conflicts of interest in this work” should read “SA has received speaker/consultancy fees from Boehringer Ingelheim, AstraZeneca, Chiesi, Teva and Novartis; non-financial support from Boehringer Ingelheim, Chiesi and Novartis; and research grants from AstraZeneca, GlaxoSmithKline and Novartis. MM has received speaker fees from Boehringer Ingelheim, Chiesi, Cipla, Menarini, Rovi, Bial, CSL Behring, Grifols and Novartis; consultancy fees from Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Bial, Gebro Pharma, CSL Behring, Laboratories Esteve, Mereo BioPharm, Verona Pharma, pH Pharma, Novartis and Grifols; and research grants from GlaxoSmithKline and Grifols. ZA has received speaker/consultancy fees from Boehringer Ingelheim, AstraZeneca, Chiesi, Teva and Novartis, GlaxoSmithKline; non-financial support from Boehringer Ingelheim, GSK and Novartis; and research grants from AstraZeneca, GlaxoSmithKline and Novartis. The authors report no other conflicts of interest in this work”.