Burden and risk factors of diabetes and hyperglycemia in India: findings from the Global Burden of Disease Study 2016

Abstract

Background

Diabetes, hyperglycemia, and their complications are a growing problem in India. However, no comprehensive picture of this disease burden has yet been presented to date.

Methods

I used aggregate data from the Global Burden of Disease 2016 to describe the burden of diabetes and its risk factors, chronic kidney disease (CKD) due to diabetes, and diseases caused by high fasting plasma glucose from 1990 to 2016 in India.

Results

Deaths due to diabetes accounted for 3.1% (95% uncertainty interval [UI]: 2.9–3.3) of all deaths in India in 2016, up from 0.98% (95% UI: 0.87–1.1) of all deaths in 1990. Diabetes and hyperglycemia accounted for 27.5 million disability-adjusted life years in 2016, of which diabetes accounted for 10 million. Diabetes contributes to the causation of ischemic heart disease, stroke, CKD, peripheral artery disease, specific cancers, and tuberculosis via intermediate hyperglycemia. High body mass index, dietary factors (diet low in fruits, nuts and seeds, and whole grains), and tobacco use were the most important risk factors for diabetes.

Conclusion

Diabetes and CKD due to hyperglycemia pose a large and increasing burden in India. Urgent programs and policies are needed to reduce the identified risk factors for diabetes and its burden.

Keywords:

• diabetes
• hyperglycemia
• mortality
• morbidity
• chronic kidney disease
• ischemic heart disease
• tuberculosis

Acknowledgments

The author thanks the Department for International Development, UK, for funding this open access publication and for funding the Global Operational Research Fellowship Programme at the International Union Against Tuberculosis and Lung Disease, Paris, France, in which the author works as a Senior Operational Research Fellow. The author also acknowledges the GBD Project collaborators for putting data in the public domain and allowing relevant analysis and interpretations to aid decision-making.

Disclosure

The author reports no conflicts of interest in this work.