Initial outcomes of one anastomosis gastric bypass at a single institution

Abstract

Introduction

One anastomosis gastric bypass (OAGB) is an emerging bariatric procedure, which has been reported to be safe and effective. This study aims to evaluate the short-term outcome of OAGB and its midterm effects on weight loss and remission of type 2 diabetes mellitus (T2DM).

Materials and methods

A retrospective review of patients who had undergone OAGB between January 2013 and January 2017 in King Abdulaziz University Hospital, Jeddah, Saudi Arabia, is presented here. Patients’ perioperative characteristics, biochemical profile (fasting blood glucose, HbA1c and iron profile) and details on subsequent weight loss in terms of body mass index (BMI) and excess weight loss percentage (EWL%) along with early and late postoperative complications were evaluated.

Results

Out of the 47 patients who underwent OAGB, 42 were included in this study and completed the 2-year follow-up. Average operative time was 107±21.3 minutes and average length of hospital stay was 2.5±0.53 days. Mean preoperative BMI was 47.6±9.1 kg/m², and at 1 and 2 years of follow–up, it was 30.5±7.4 and 27.1±5.1, respectively. No mortality, anastomotic leak or bleeding were reported. Most common midterm complication was iron deficiency anemia (n=7/42). Remission of T2DM at 6 months was 80%. Patients with preoperative T2DM for less than 10 years showed better remission (P<0.001).

Conclusion

Our analysis suggests that OAGB is a safe and effective weight loss procedure that carries low perioperative risk and acceptable nutritional complications in the midterm, with a notable remission of T2DM. Preoperative duration of T2DM plays a major role in achieving remission after OAGB.

Keywords:

• bariatric surgery
• weight loss
• diabetes mellitus
• mini gastric bypass
• single anastomosis gastric bypass
• omega loop gastric bypass

Acknowledgments

We would like to thank Charles V. Rajadurai, and Anoud R. Omer who helped us with editing and revising the manuscript, Afnan H. Altowaireb, Esraa Alzahrani and Ibtihal A. Alghamdi for their contribution in collecting the data. This research was self-funded and received no grant from any funding agency.

Author contributions

As per the guidelines of the International Committee of Medical Journal Editors (ICMJE), all authors made substantive intellectual contributions to the study, collaboratively designing, analyzing, and interpreting the data, and writing and revising the manuscript. All authors gave final approval of the version to be published, and agree to be accountable for all aspects of the work.

Disclosure

The authors report no conflicts of interest in this work.