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Original Research

Molecular network topology and reliability for multipurpose diagnosis

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Pages 2385-2392 | Published online: 19 Oct 2011
 

Abstract

This investigation proposes the use of molecular network topology for drug delivery and diagnosis network design. Three modules of molecular network topologies, such as bus, star, and ring networks, are designed and manipulated based on a micro- and nanoring resonator system. The transportation of the trapping molecules by light in the network is described and the theoretical background is reviewed. The quality of the network is analyzed and calculated in terms of signal transmission (ie, signal to noise ratio and crosstalk effects). Results obtained show that a bus network has advantages over star and ring networks, where the use of mesh networks is possible. In application, a thin film network can be fabricated in the form of a waveguide and embedded in artificial bone, which can be connected to the required drug targets. The particular drug/nutrient can be transported to the required targets via the particular network used.

Acknowledgments

The authors would like to thank the Institute of Advanced Photonics Science, Nanotechnology Research Alliance, University of Technology Malaysia, Malaysia, and King Mongkut’s Institute of Technology, Thailand, for providing the research facilities. This research was supported by the University of Technology Malaysia’s Tier 1/Flagship Research Grant, MyBrain15 Fellowship/MOHE SLAB Fellowship, and a Ministry of Higher Education research grant.

Disclosure

Other than the support received outlined in the Acknowledgments, the authors have no conflicts of interest to declare in this work.