Recent advance on the antitumor and antioxidant activity of grape seed extracts

Abstract:

The grape pomace (including seeds and stems) poses potential disposal and pollution problems along with loss of valuable biomass and nutrients. The utilization of grape seeds processing as a source of functional ingredients is a promising field. Grape seed extract provides a concentrated source of polyphenols. Grape seed extract is known as an effective antioxidant that protects the body from premature aging and disease. A number of phytochemicals including resveratrol, proanthocyanidins, etc, have demonstrated significant benefits in cancer chemoprevention. In this review, we summarize the existing knowledge on the antitumor and antioxidant activity of grape seeds polyphenols.

Keywords::

• grape seed
• antitumor activity
• antioxidant activity
• polyphenol
• proanthocyanidin

Acknowledgments

This research was supported by National Natural Science Foundation of China (project code: 31470542) and Natural Science Foundation of Hebei Province, People’s Republic of China (project code: C2014407059).

Disclosure

The authors have declared that there is no conflicts of interest.