Effectiveness of Dupilumab for an Elderly Patient with Prurigo Nodularis Who Was Refractory and Contradicted to Traditional Therapy

Abstract

Prurigo nodularis (PN) is an intense pruritic skin condition. Treatment of PN is challenging. We described an elderly patient with PN who had contradictions of cyclosporine or methotrexate and achieved significant improvement after treatment with dupilumab. We also reviewed published cases of elderly patients with PN who were refractory to traditional therapy.

Keywords:

• prurigo nodularis
• dupilumab
• elderly patient
• targeted therapy

Acknowledgments

This work was supported by the National Natural Science Foundation of China (81972931 to HF), and the Medical and Health Science and Technology Project of Health Commission of Zhejiang Province (2020KY558 to JQ).

Disclosure

The authors declare no conflicts of interest related to this work.