Abstract
Introduction
Asthma is a chronic lung illness marked by a reversible airway blockage. Both genetic and environmental factors influence higher asthma rates. The present study aims to assess the various socio-demographic and environmental factors influencing the causation of childhood asthma among patients attending the Paediatric Department of Gauhati Medical College and Hospital (GMCH), Assam.
Materials and Methods
A total of 150 clinically diagnosed asthma patients of 3–12 years as cases and patients of the same age group free from respiratory diseases with no history of asthma in a 1:1 ratio as controls were selected. A predesigned and pretested proforma was used to collect data, and written informed consent was obtained from all the legal guardians of the participants. Data were analyzed by chi-square test and binary logistic regression using SPSS V20, considering a p-value <0.05 significant.
Results
Urban and male children were found to be at higher risk of developing asthma. Children belonging to the urban locality (OR= 4.53; 95% CI: 1.57–13.09; p<0.05), damp environment (OR= 5.21; 95% CI: 1.23–22.10; p<0.05), lower socioeconomic status (OR= 3.48; 95% CI: 1.34–9.01; p<0.05), presence of pets (OR= 6.77; 95% CI: 1.76–25.99; p<0.05), family history of atopy/ allergy (OR= 43.29; 95% CI: 5.80–323.15 p<0.05), smoking/passive smoking (OR=23.54; 95% CI: 1.41–394.21 p<0.05) and mixed feeding (OR= 4.47; 95% CI: 1.46–13.63 p<0.05) were the significant risk factors of childhood asthma.
Conclusion
Children are vulnerable to environmental-induced asthma. Awareness and preventive measures are necessary to control and reduce the burden of childhood asthma.
Ethics
All data were treated confidentially, and the study was conducted following the Declaration of Helsinki.
Acknowledgments
Thanks to all the faculty members of the paediatric department who have helped collect the data and evaluate its intellectual content. All departmental colleagues who helped us access the departmental library and settings during the study were also acknowledged.
Author Contributions
All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; they took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.
Disclosure
The authors report that there are no conflicts of interest in this work.