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RESEARCH LETTER

Impact of Baseline Lung Function on Future Exacerbations in Patients with Moderate-to-Severe Asthma

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Pages 1639-1644 | Received 20 May 2022, Accepted 30 Sep 2022, Published online: 11 Nov 2022
 

Data Sharing Statement

The datasets used and/or analysed during the current analysis are available from the corresponding author on reasonable request.

Ethics Approval

This study is based in part on data from the Clinical Practice Research Datalink (CPRD) obtained under license from the UK Medicines and Healthcare products Regulatory Agency. The anonymized data are provided by patients and collected by the NHS as part of their care and support. The interpretation and conclusions contained in this study are those of the author/s alone. The CPRD has ethics approval from the Health Research Authority to support research using anonymized patient data. This study received protocol approval (ISAC 17_077) from the CPRD Independent Scientific Advisory Committee. The study was conducted in accordance with the principles of the Declaration of Helsinki.

Acknowledgments

The research was sponsored by Sanofi and Regeneron Pharmaceuticals, Inc. Medical writing/editorial assistance was provided by Vatsal Vithlani (M.Pharm) and Amit Garg (M.Pharm) of Sanofi, according to the Good Publication Practice guideline.

Author Contributions

All authors contributed to data analysis, drafting, or revising the article, have agreed on the journal to which the article will be submitted, gave final approval of the version to be published, and agree to be accountable for all aspects of the work.

Disclosure

Khan AH, Gray C, Eckert L, Amand C and Rowe PJ are employees of Sanofi, may hold stock and/or stock options in the company. Maroni J and Wang Z are employees of Regeneron Pharmaceuticals Inc, may hold stock and/or stock options in the company. Jones B, Berni T and Morgan CL are employees of Pharmatelligence, which was funded by Sanofi to conduct the study. The authors report no other conflicts of interest.

Additional information

Funding

The study was funded by Sanofi and Regeneron Pharmaceuticals Inc.