Platelet Count and Bleeding in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism: Lesson from the RIETE Registry

Abstract

Major bleeding is one of the most dangerous complications for patients undergoing anticoagulant treatment for VTE. Several clinical scores have been planned to identify patients at higher risk of bleeding, and most of them take into consideration the number of platelets in particular if lower than normal. Here we report the clinical experience made with the RIETE registry concerning anticoagulant treatment in the presence of different values of platelets and their related risk of bleeding.

Keywords:

• thrombocytopenia
• venous thromboembolism
• bleeding
• bleeding risk

Ethics

The authors certify that institutional approval is not required by their Institutions, because the intellectual property of reported data is of the RIETE registry; ethic committee that approved the RIETE registry in Fatebenefratelli Hospital of Naples was “Comitato Etico Lazio1”.

Disclosure

Professor Manuel Monreal reports grants and personal fees from Sanofi, grants from Bayer, and personal fees from Leo, during the conduct of the study. The authors report no other conflicts of interest in this work.