A Case of Ulcerative Colitis Induced by Paraneoplastic Syndrome?

Abstract

Background

Paraneoplastic syndromes often cause endocrine, neurological, cutaneous, and hematologic pathologies, and cases with digestive symptoms as prominent cases are rare.

Case Description

A 1-year-old child admitted to the emergency department with severe abdominal distension was later diagnosed with sacrococcygeal yolk cystoma with ulcerative colitis. After symptomatic management, surgical removal of the tumor, and JEB chemotherapy, the symptoms of ulcerative colitis disappeared completely. After 7 years of follow-up, the child grew and developed well, and there was no recurrence of tumor and ulcerative colitis.

Conclusion

Yolk sac tumor with ulcerative colitis is a rare paraneoplastic syndrome with complex clinical manifestations.

Keywords:

• children
• paraneoplastic syndrome
• toxic megacolon
• ulcerative colitis
• yolk sac tumor

Ethics Approval and Consent to Participate

This study was conducted in accordance with the declaration of Helsinki. This study was conducted with approval from the Ethics Committee of Anhui Provincial Children’s Hospital, Children’s Hospital of Fudan University. A written informed consent was obtained from legal guardians of all participants.

Consent for Publication

Consent for publication was obtained from every individual (there parents) whose data are included in this manuscript.

Disclosure

The authors report no conflicts of interest in this work.

Additional information

Funding

Scientific research project of Anhui Provincial Health Commission (AHWJ2021a025).