Sleep disturbances in Parkinson’s disease patients and management options

Abstract

Sleep disturbances are among the most common nonmotor complaints of patients with Parkinson’s disease (PD), and can have a great impact on quality of life. These disturbances manifest in a variety of ways; for instance, insomnia, sleep fragmentation, and excessive daytime sleepiness. Sleep-related movement disorders such as restless legs syndrome and periodic leg movements may share a common pathophysiology, and occurrence of rapid eye movement behavior disorder may predate the onset of PD or other synucleinopathies by several years. Medications for PD can have a significant impact on sleep, representing a great challenge to the treating physician. Awareness of the complex relationship between PD and sleep disorders, as well as the varied way in which sleep disturbances appear, is imperative for successful long-term management.

Keywords:

• sleep disorders
• insomnia
• restless legs syndrome
• Parkinson disease
• fatigue
• REM behavior disorder

Acknowledgment

The authors thank Dr Arthur Walters for review and guidance with the creation of the manuscript, along with the template for the appendix.

Disclosure

The authors report no conflicts of interest in this work.