Physical activity and sedentary behavior in patients with systemic lupus erythematosus and rheumatoid arthritis

Abstract

Objective

Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are at increased risk of cardiovascular disease (CVD). As sedentary behavior and lack of physical activity are known cardiovascular risk factors, we compared habitual activity between SLE patients, RA patients, and healthy control participants.

Patients and methods

For this cross-sectional study, RA and SLE patients were recruited from rheumatology clinics at an academic medical center from April 2013 to December 2014. Healthy control participants were recruited through local advertising during the same time period. Habitual activity was measured using a triaxial accelerometer worn during waking hours for 7 consecutive days. Minutes per day of sedentary, light, and moderate–vigorous physical activity (MVPA) were recorded and compared between SLE, RA, and healthy participants using ANOVA.

Results

There were 59 participants included in the analysis: 20 SLE patients, 19 RA patients, and 20 healthy controls. Disease activity was quiescent in both the SLE and RA groups. All three groups demonstrated high sedentary behavior (mean ± SD sedentary time for all participants: 10.1±1.3 hours/day; 76.4% total wear time). There were no significant differences between SLE, RA, and healthy participants in time spent in sedentary behavior (p=0.80) or light activity (p=0.17). Total MVPA (mean ± SD, minutes/day) was significantly lower in SLE (34.5±22.7; p<0.001) and RA (41.5±21.3; p=0.005) patients compared to controls (64.9±22.4).

Conclusion

SLE and RA patients demonstrate suboptimal MVPA despite well-controlled disease. Given their increased CVD risk, effective interventions are required to improve habitual physical activity levels in both populations.

Keywords:

• systemic lupus erythematosus
• rheumatoid arthritis
• physical activity
• sedentary behavior
• accelerometry

Acknowledgments

The abstract of this paper was presented at the 2016 ACR Annual Meeting as a poster presentation with interim findings. The poster’s abstract was published in “2016 ACR/ARHP Annual Meeting Abstract Supplement” in Arthritis & Rheumatology (DOI: 10.1002/art.39977). Support for this work was provided by the John & Marian Quigley Endowment Fund for Rheumatology.

Disclosure

The authors report no conflicts of interest in this work.