Brittle cornea syndrome: current perspectives

Abstract

Brittle cornea syndrome (BCS) is a rare autosomal recessive connective tissue disorder characterised by severe corneal thinning, with the major ocular risk being spontaneous ocular perforation due to progressive stromal thinning and ectasia. It is a complex condition with limited treatment options. The purpose of this review is to highlight the difficulties associated with the condition and examine the available published evidence with regards to management.

Keywords:

• brittle Cornea
• spontaneous corneal perforation
• corneal ectasia

Disclosure

The authors report no conflicts of interest in this work.