Unilateral rhino–orbital–cerebral mucormycosis with contralateral endogenous fungal endophthalmitis

Abstract

Rhino–orbital–cerebral mucormycosis (ROCM) is an uncommon but fatal fungal infection. We report a rare case of unilateral ROCM with ipsilateral central retinal artery occlusion and contralateral choroiditis, which later progressed to endogenous fungal endophthalmitis. The patient was successfully treated with sinuses debridement, systemic liposomal amphotericin B, and intravitreal amphotericin B. The endophthalmitis completely resolved with good vision, but the ROCM eye remained blind due to central retinal artery occlusion.

Keywords:

• rhino–orbital‒cerebral mucormycosis
• central retinal artery occlusion
• chorioditis
• endogenous fungal endophthalmitis
• Rhizopus

Acknowledgments

This case report received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Disclosure

The authors report no conflicts of interest in this work.