Abstract
Background
Improper use of bronchodilators is associated with poor disease control, nonadherence to long-term therapy, and poor clinical outcomes. Our current understanding of factors associated with correct inhaler use and adherence is limited. We measured physician-and patient-reported confidence in device usage and associations with treatment adherence and COPD-related health status.
Methods
This was an analysis of a US observational, point-in-time survey of physicians and patients. Physicians who met study eligibility criteria completed surveys for 5 consecutive, eligible patients who were then invited to respond to questionnaires. We assessed patient demographics, type of prescribed inhaler device(s), device training, COPD severity, comorbidities, physician-and patient self-reported confidence in device usage, treatment adherence, and health status.
Results
Completed questionnaires for 373 patients were provided by 134 physicians. Complete confidence in device usage was observed for 22% and 17% of patients as reported by patients and physicians, respectively. Greater confidence was associated with higher self-reported adherence to inhaler usage. Physicians were more likely than patients to report lower levels of patient confidence in device usage. High physician- and patient-reported confidence were associated with more favorable health status. Predictors of confidence in device usage included fewer comorbidities, no depression, and higher education levels.
Conclusion
Low confidence in inhaler usage was associated with lower adherence and poor COPD-related health status. Choice of inhaler device tailored to patients’ ability to use specific devices and ongoing education to support optimal inhaler usage may improve patient confidence and enhance both adherence and health status.
Acknowledgments
This study was supported by Sunovion Pharmaceuticals Inc. Medical writing support was provided by Carole Alison Chrvala, PhD of Health Matters, Inc, funded by Sunovion Pharmaceuticals Inc.
Data collection was undertaken by Adelphi Real World as part of a syndicated survey, entitled the Respiratory Disease Specific Programme, sponsored by multiple pharmaceutical companies of which one was Sunovion Pharmaceuticals Inc. Sunovion Pharmaceuticals Inc. did not influence the original survey through either contribution to the design of questionnaires or data collection. The study described here using data from the Respiratory Disease Specific survey was funded by Sunovion Pharmaceuticals Inc.
Disclosure
ANA is on the speaker’s bureau for Sunovion Pharmaceuticals Inc. VG is an employee of Sunovion Pharmaceuticals Inc. AR is an employee of Adelphi Real World. MS is an employee of Adelphi Real World. The authors report no other conflicts of interest in this work.