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Original Research

Medication Adherence and Coping with Disease in Patients from a Neurological Clinic: An Observational Study

ORCID Icon, , & ORCID Icon
Pages 1439-1449 | Published online: 28 Jun 2021
 

Abstract

Purpose

Medication non-adherence is a huge concern for the medical community. For chronic, especially neurological diseases, taking medication is a central pillar of treatment. To improve adherence to these oftentimes complex medication regimens, the construct needs to be understood in more depth. The aim of this study was to investigate associations between adherence with sociodemographics, clinical variables, and coping in neurological patients.

Patients and Methods

The sample consisted of 545 patients from a German neurological clinic. Adherence was assessed with the Stendal Adherence to Medication Score (SAMS). Patients were grouped as completely adherent (SAMS = 0), non-adherent (upper 25% of the sample), and moderately adherent. Associations with coping were assessed using the Essen Coping Questionnaire.

Results

Medication adherence was low compared to other non-neurological patient samples. Differences between adherence groups were found regarding gender and facets of coping, namely “trivialisation, wishful thinking and defence” and “finding of inner stability”.

Conclusion

Interventions to improve medication adherence should focus on facets of coping with disease, increasing acceptance of disease, willpower, and confidence in treatment.

Disclosure

Dr Tino Prell reports grants from Bundesministerium für Bildung und Forschung (BMBF), during the conduct of the study (01GY1804). The authors report no conflicts of interest in this work.