Hypervalent iodine reagents for heterocycle synthesis and functionalization

Abstract:

Hypervalent iodine reagents have been vastly applied in many significant oxidative reactions. This surging interest in iodine reagents is mainly due to the very useful oxidizing properties, combined with their benign environmental character and commercial availability. In this review, we focus on the representative transformations that used the common hypervalent iodine reagents as oxidants in heterocycle synthesis and functionalizations, based on the type of the hypervalent iodine reagents.

Keywords::

• hypervalent iodine reagent
• heterocycle synthesis
• heterocycle functionalization
• oxidative reaction

Acknowledgments

We acknowledge the National Natural Science Foundation of China (#21472136), Tianjin Research Program of Application Foundation and Advanced Technology (#15JCZDJC32900), and the National Basic Research Project (2014CB932201) for financial support.

Author contributions

All authors contributed toward data analysis, drafting and critically revising the paper and agree to be accountable for all aspects of the work. All authors read and approved the final version of the manuscript.

Disclosure

The authors report no conflicts of interest in this work.