Diclofenac gel in the treatment of actinic keratoses

Abstract

Actinic keratoses are areas of intraepithelial neoplasia for which treatment is necessary. Because they arise in areas of sun damage, it is desirable to treat the entire damaged field to not only treat visible lesions, but also subclinical, emerging malignancies, ie, “field therapy”, 5-fluorouracil, imiquimod, and diclofenac are all treatment options, and are discussed and compared.

Keywords:

• actinic keratosis
• topical diclofenac
• field therapy
• review

Disclosure

The author serves as a consultant for Graceway Pharmaceuticals, Inc and Pharmaderm, a division of Nycomed US. Otherwise the author reports no conflicts of interest in this work.