A Case of Superficial Kaposiform Hemangioendothelioma Treated with Oral Propranolol Combined with Topical Sirolimus

Abstract

Kaposiform hemangioendothelioma(KHE) without Kasabach-Merritt phenomenon is a rare tumor primarily observed in pediatric patients; however, its documentation in the literature remains limited. We reported about a 1-year-old boy diagnosed with superficial KHE who received oral propranolol in combination with topical sirolimus and reviewed relevant reports and treatment of superficial KHE.

Keywords:

• superficial kaposiform hemangioendothelioma
• pediatric patients
• rare tumor
• case treatment

Abbreviations

KHE, Kaposiform hemangioendothelioma; KMP, Kasabach-Merritt phenomenon; MRI, Magnetic resonance imaging; VEGF, Vascular endothelial growth factor.

Data Sharing Statement

The data that support the findings of this study are available on request from the corresponding author upon reasonable request.

Ethics Approval and Consent

All treatment plans were approved by the Ethics Research Association of the Children’s Hospital of Zhejiang University School of Medicine. The Ethics Research Association of Children’s Hospital of Zhejiang University School of Medicine granted approval for the publication of the case details.

Consents Statement

Written informed consent was obtained from the minors’ legal guardian/next of kin for the publication of any potentially identifiable images or data included in this article.

Acknowledgment

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Disclosure

The authors report no conflicts of interest in this work.

Additional information

Funding

There was no source of funding for this study.