Acknowledgements
We thank Drs Paul Brookes and George Porter for their comments on our manuscript.
Financial & competing interests disclosure
This work was supported by NIH grants HL33333 (to Shey-Shing Sheu), AR044657 (to Robert Dirksen), Chinese National Natural Science Foundation and Major State Basic Research Development Programs of China (to Heping Cheng). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.