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Clinical Lipidology Volume 7, 2012 - Issue 1
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Assessing omega-3 fatty acid supplementation during pregnancy and lactation to optimize maternal mental health and childhood cognitive development

Chelsea M KlemensMichigan State University, College of Human Medicine, East Lansing, MI 48824, USA
,
Kataneh SalariUniversity of MichiganDivision of Maternal–Fetal Medicine,Department of Obstetrics & Gynecology, F4835, Box 0264 Mott Hospital, 1500 E Medical Center Drive, Ann Arbor, MI 48109-0264, USA
&
Ellen L MozurkewichI University of New Mexico,AlbuquerqueDivision of Maternal–Fetal Medicine,Department of Obstetrics & Gynecology, Albuquerque, NM 87131-0001, USATel.: +1 734 764 1406Fax: +1 734 647 1006 [email protected]Correspondence [email protected]
Pages 93-109 | Published online: 18 Jan 2017
 
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Abstract

The omega-3 fatty acid, docosahexaenoic acid, is an important building block of the CNS, and its availability during pregnancy and lactation may influence maternal mental health and, later, childhood developmental outcomes. Epidemiological and observational studies have supported a role for omega-3 fatty acids in optimizing child development and maternal mental health. However, results of randomized intervention studies have not consistently shown beneficial effects for omega-3 fatty acid supplementation during pregnancy and lactation. This review summarizes the biological plausibility, as well as the available evidence from observational and randomized controlled trials, of omega-3 supplementation in pregnancy and lactation.

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