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Abstract
Evaluation of: Markaki I, Nilsson U, Kostulas K, Sjöstrand C. High cholesterol levels are associated with improved long-term survival after acute ischemic stroke. J. Stroke Cerebrovasc. Dis. 23(1), e47–e53 (2014). Although high serum cholesterol concentration is a well-known risk factor of atherosclerosis, which is one of the major causes of ischemic cerebral stroke, some studies suggested that low cholesterol levels are associated with poor outcome in patients after stroke. In the evaluated study, the relationship between cholesterol level measured on admission to the hospital in patients with ischemic stroke and long-term mortality was evaluated. It was demonstrated that total serum cholesterol concentration higher than 4.6 mM was an independent predictor of lower mortality within the observation period (median: 30 months). These results suggest the ‘reverse epidemiology’ phenomenon, with regard to serum cholesterol, in acute stroke survivors.