Financial & competing interests disclosure
Support for this work was provided by the UK National Institute for Health Research UCLH Biomedical Research Center (BRC84/CN/SB/5984) and the H2020 Project MultipleMS (733161). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.