https://orcid.org/0000-0001-8931-8995
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Abstract
Objective: To conduct a systematic review and meta-analysis on the prediction of severity of gastric intestinal metaplasia (GIM) in localized and entire gastric mucosa using endoscopy. Methods: The authors searched Web of Science, PubMed, Embase and Cochrane Central Register of Controlled Trials and performed systematic searches on endoscopic grading of GIM of the entire stomach using Meta-DiSc and Stata. Results: Sensitivity and specificity for the stratified prediction of overall GIM were 0.91 (95% CI: 0.85–0.95) and 0.91 (95% CI: 0.88–0.93), respectively. Sensitivity in predicting the different grades of GIM was higher in operative link on GIM assessment grades 0, III and IV but lower in grades I and II. Conclusion: Digital chromoendoscopy is well suited to predicting the severity of localized and overall GIM.
Author contributions
Conception and design: N Wei and R Shi. Collection and assembly of data: N Wei, M Zhou, S Lei and L Yang. Data analysis and interpretation: M Zhou, S Lei and Z Duan. Manuscript writing: N Wei, L Yang, Z Duan, Y Zhang, Z Zhong and Y Liu. Final approval of manuscript: All authors. Accountable for all aspects of the work: All authors.
Financial & competing interests disclosure
This study was supported by Jiangsu Provincial Health and Family Planning Commission, ‘Strong Sanitation Project’: Esophageal Innovation Team. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.