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Meta-Analysis

Radiofrequency ablation versus stereotactic body radiation therapy for hepatocellular carcinoma: a meta-regression

, , ORCID Icon, , & ORCID Icon
Pages 279-287 | Received 09 Sep 2022, Accepted 31 Jan 2023, Published online: 14 Mar 2023
 

Abstract

Aim: The aim of this meta-regression was to assess the impact of mean/median age, mean/median tumor size, percentage of males in total sample, and total sample size on the comparative effectiveness of radiofrequency ablation (RFA) and stereotactic body radiation therapy (SBRT). Methods: Ten studies reporting on the composite outcome of overall survival and local control were included. Results: A significant relationship was found between age and overall survival at 1 and 2 for both RFA and SBRT. A significant relationship was noted also between age and local control at 1 and 2 years for RFA. Conclusion: Patients treated with SBRT had a wider range of tumor sizes and larger tumor sizes; no relationship was observed between tumor size and overall survival or local control by SBRT.

Supplementary data

To view the supplementary data that accompany this paper please visit the journal website at: www.tandfonline.com/doi/suppl/10.2217/fon-2022-0893

Financial & competing interests disclosure

This research was funded, in part, through the NIH/NCI Cancer Center Support Grant P30 CA008748. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

Additional information

Funding

This research was funded, in part, through the NIH/NCI Cancer Center Support Grant P30 CA008748. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

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