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Abstract
During the last decade, several successes have been achieved in the field of vaccinology that maintain its paramount position as the leading hope for the treatment of most acute and chronic diseases worldwide. However, challenges remain at both the logistic and the scientific level. The fourth edition of New Generation Vaccines updates the reader concerning recent scientific and clinical advances in vaccinology, clearly framing the discussion in the context of future challenges and the corresponding strategies regarding how to pursue the solutions.