Nanomedicine Strategies for Targeting Skin Inflammation

Abstract

Topical treatment of skin diseases is an attractive strategy as it receives high acceptance from patients, resulting in higher compliance and therapeutic outcomes. Recently, the use of variable nanocarriers for dermal application has been widely explored, as they offer several advantages compared with conventional topical preparations, including higher skin penetration, controlled and targeted drug delivery and the achievement of higher therapeutic effects. This article will focus on skin inflammation or dermatitis as it is one of the most common skin problems, describing the different types and causes of dermatitis, as well as the typical treatment regimens. The potential use of nanocarriers for targeting skin inflammation and the achievement of higher therapeutic effects using nanotechnology will be explored.

Keywords::

• animal models
• dermatitis
• glucocorticoids
• hair follicles
• nanoparticles
• skin inflammation
• skin penetration
• targeting

Financial & competing interests disclosure

The authors would like to gratefully acknowledge financial support from the EuroNanoMed project ‘CheTherDel’ (2011-ERNA-001-06). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

Additional information

Funding

The authors would like to gratefully acknowledge financial support from the EuroNanoMed project ‘CheTherDel’ (2011-ERNA-001-06). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.