Financial & competing interests disclosure
This work was supported by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health under award numbers R01NS113823 and R01NS065257. DP Turner and LR Leffert have no relevant financial disclosures. TT Houle has received consultancy fees from GlaxoSmithKline and Eli Lily & Company and grant funding from Teva Pharmaceuticals and is the owner of StatReviewer. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.