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Original Article

Concentration of Malignant Cells from Vaginal Washings by Means of a New Type of Centrifuge

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Pages 393-415 | Published online: 09 Jul 2009
 

Abstract

A new type of centrifuge has been applied to the isolation and concentration of malignant cells obtained from cases of untreated invasive carcinoma of the cervix and uterus. It has been proved that the malignant cells do not lose their cytological identity during centrifugal fractionation of the solid elements obtained by vaginal washings. Diagnostically important cells have been satisfactorily separated from erythrocytes, mucus, detritus, and bacteria, and concentrated together with some other cells having the same specific gravity and/or size. Microscopic slides prepared by the technique described have facilitated identification of the malignant cells.

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