Abstract
The effects of various chemotherapeutic drugs on the squamous epithelium of the cervicovaginal tissues were investigated in a test group of 74 and a control group of 44 women with advanced extragenital malignancy. The cyto-logical findings were as follows
(A) cytohormonal changes reflecting estrogenic withdrawal in pre- and postmenopausal women
(B) reversible cytopathol'ogical changes reflecting a cytotox-ic reaction, and
(C) absence of premalignant and malignant changes.