Abstract
Survival after treatment of stage 1 endometrial ad-enocarcinoma was studied in a material of 111 patients, median follow-up period 6 years.
Routine treatment was preoperative intrauterine and vaginal radium followed, in 6 weeks, by total hysterectomy and bilateral salpingo-oophorectomy.
The 5-year corrected survival after treatment by operation and/or irradiation was 93%, after irradiation alone 87%. A significantly better survival was found in stage la (95%) than in stage Ib (83%) and also in patients with grade 1 tumors (97%) than in those with grade 3 tumors (71%). 21% of the patients had a residual endometrial tumor after preoperative radium, and among them survival was signifi-canctly lower than in patients without residual tumor. The recurrence rate was 11.7%. Vaginal metastases did not occur.
Our routine treatment afforded satisfactory results in stage 1, grade 1 and 2. However, supplementary treatment must be recommended in the case of grade 3 tumors, of myometrial deep invasion, and of residual tumor following preoperative radium therapy.