Interaction Between Prostaglandin E₂ and Noradrenalin on Collagen Synthesis in Human Cervical Tissue During Pregnancy

A. Norström Department of Obstetrics and Gynecology, University of Gothenburg, Gothenburg, Sweden

J. Tjugum Department of Obstetrics and Gynecology, University of Gothenburg, Gothenburg, Sweden

L. Wilhelmsson Department of Obstetrics and Gynecology, University of Gothenburg, Gothenburg, Sweden

L. Hamberger Department of Obstetrics and Gynecology, University of Gothenburg, Gothenburg, Sweden

Abstract

The effects of prostaglandin E₂ (PGE₂) and noradrenalin (NA) on the incorporation of [³H]proline in cervical tissue of pregnant women were investigated. NA inhibited the incorporation in early as well as in term pregnancy. PGE₂ counteracted the NA-effect in the former group of patients but did not affect the influence of NA at term. the results demonstrate an interaction between PGE₂ and NA and point to a hitherto unknown effect of NA in the regulation of cervical connective tissue metabolism.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Interaction Between Prostaglandin E₂ and Noradrenalin on Collagen Synthesis in Human Cervical Tissue During Pregnancy

Information for

Open access

Opportunities

Help and information

Interaction Between Prostaglandin E2 and Noradrenalin on Collagen Synthesis in Human Cervical Tissue During Pregnancy

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature

Interaction Between Prostaglandin E₂ and Noradrenalin on Collagen Synthesis in Human Cervical Tissue During Pregnancy