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Acta Obstetricia et Gynecologica Scandinavica Volume 66, 1987 - Issue 1
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Original Article

Single Dose Bromocriptine Microcapsules in Postpartum Lactation Inhibition

Lars Svanberg Department of Obstetrics and Gynecology, Malmö General Hospital, University of Lund, Malmö, Sweden; Department of Neuroendocrinology, Clinical Research, Sandoz Ltd., Basel; Sandoz AB, Sweden, and East Hospital, University of Gothenburg, Sweden
,
Ioana Lancranjan Department of Obstetrics and Gynecology, Malmö General Hospital, University of Lund, Malmö, Sweden; Department of Neuroendocrinology, Clinical Research, Sandoz Ltd., Basel; Sandoz AB, Sweden, and East Hospital, University of Gothenburg, Sweden
,
TorbjÖRn Arvidsson Department of Obstetrics and Gynecology, Malmö General Hospital, University of Lund, Malmö, Sweden; Department of Neuroendocrinology, Clinical Research, Sandoz Ltd., Basel; Sandoz AB, Sweden, and East Hospital, University of Gothenburg, Sweden
&
BjÖRn Andersch Department of Obstetrics and Gynecology, Malmö General Hospital, University of Lund, Malmö, Sweden; Department of Neuroendocrinology, Clinical Research, Sandoz Ltd., Basel; Sandoz AB, Sweden, and East Hospital, University of Gothenburg, Sweden
Pages 61-62 | Received 11 Nov 1985, Accepted 12 Mar 1986, Published online: 03 Aug 2009
 

Abstract

The clinical efficacy and safety of a single intra-muscular injection of ParlodelR LA, PravidelR 50 mg, were Studied in the prevention of lactation in 10 postpartum women.

The overall efficacy at the end of the 28 day observation period was very good in 8 postpartum women and good in 2 women and no rebound lactation occurred. The prolactin Aasma levels decreased to normal levels within 4 days in 9 women. Menstrual bleeding occurred in 9 women 4 to 6 weeks after treatment. Laboratory data recorded in this study support that PravidelR is effective in suppressing postmartum lactation.

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