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Original Article

Calcitonin Secretion by Human Placental Tissue

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Pages 323-326 | Received 01 Mar 1986, Accepted 04 Sep 1986, Published online: 03 Aug 2009
 

Abstract

We have investigated the synthesis in vitro of calcitonin (CT) by human placenta at.term. Separate placental tissue samples were incubated in culture medium with various Ca concentrations for 6 h. The CT concentrations in the medium were determined by radio-immunoassay. In addition the effect of DB-cAMP on the synthesis was also studied. We could demonstrate CT secretion in all experiments. The CT concentrations were determined by two different antibodies. Both antibodies registered the CT secretion. Addition of DB-cAMP to the culture medium stimulates the synthesis.

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